Showing posts with label Parkinson's disease. Show all posts
Showing posts with label Parkinson's disease. Show all posts

Friday, December 27, 2013

Flight attendants worry about risk of Parkinson's disease

More and more flight attendants report health effects from chemical exposure.
Flight attendants fear they could have been put at risk of long-term brain disorders including Parkinson's disease by regular exposure to insecticides sprayed on long-haul flights.

Five flight attendants who have developed Parkinson's have contacted law firm Turner Freeman to ask about taking legal action against the Commonwealth government, which requires the spraying in line with World Health Organisation guidelines to prevent the spread of potentially deadly mosquito-borne viruses.

The Daily Telegraph reported the case of former Qantas steward Brett Vollus, who has been diagnosed with Parkinson's, a degenerative brain condition that can severely impact on a person's ability to control their own movements.

Turner Freeman lawyer Tanya Segelov said she was investigating a claim on Mr Vollus' behalf.

“When Brett was diagnosed, his neurologist asked him what he did, and he said he worked for Qantas, and his response was: 'Oh, another one,' ” she said.

“We have now had four more long-haul flight attendants come forward this morning, and I think we are going to see more and more people coming out of the woodwork.”

Ms Segelov said that, until about the turn of the century, the government had mandated that all spraying had to be done while aircraft were full, whereas, now, at least for flights coming in to Australia, it was done before passengers boarded.

“We need to know why the government mandated that spraying on board, and why they switched,” she said.

Evidence needed

But there is little evidence proving that regular, low-level spraying with insecticide could cause Parkinson's disease.

The World Health Organisation is reviewing the chemicals used in insecticides sprayed on aircraft. But its last review of the available research, published in 2005, concluded that, while unnecessary exposure to the chemicals should be avoided, there was no evidence of long-term risk.

“They do not pose any significant health risk when they are used in compliance with their directions for use, which are intended to limit human exposure within the levels recommended for their specific applications,” the report found.

Parkinson's expert Kay Double, from the University of Sydney Medical School and Neuroscience Research Australia, said epidemiological evidence was beginning to emerge linking pesticides and herbicides to increased risks for Parkinson's disease.

“Most of the research is on farmers, who are using it in higher concentration, but are also using it in much more open spaces,” she said. “This is a relatively new suggestion; it's not something that has been around a long time.”

Associate Professor Double said, in her opinion, the evidence that exposure could cause Parkinson's was “tenuous”.

“Exposure to environmental toxins could contribute to it, but it's unlikely that it's going to make you get Parkinson's,” she said. “Being able to prove it scientifically or legally would be very difficult.”

A spokeswoman for the federal Department of Health said aircraft were treated with insecticides because Australia is free from several very serious diseases, including yellow fever and malaria.

“If any of these diseases became established in Australia, they could have a devastating effect on our community, as these diseases cause significant numbers of deaths and illness in many other countries,” she said.

Source: Sydney Morning Herald

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Monday, November 21, 2011

Occupational chemical exposure linked to Parkinson’s risk

TCE is widely used as a metal degreasing agent.
If your work exposes you to solvents such as trichloroethylene (TCE) and perchloroethylene (PERC), you could be at a higher risk for developing Parkinson’s disease, a new research report found.

A NIH (National Institutes of Health)-funded study looked at twins, where one of the pair had developed the disorder and assessed their exposure to six chemicals previously linked to Parkinson’s disease.

The researchers concluded that two common chemical solvents, trichloroethylene (TCE) and perchloroethylene (PERC), are significantly linked to development of this disease.

The study appears in the Nov. 14, 2011 issue of Annals of Neurology.

What is Parkinson’s disease?

Parkinson's disease is a movement disorder caused by the loss of brain cells that produce a molecule called dopamine.

Health symptoms of Parkinson's include tremor, stiffness, slowed movement and impaired balance, and as these symptoms progress, patients may also develop difficulty walking, speaking or completing other activities of daily living.

Genes play a role in Parkinson's disease, but fewer than 10 percent of cases are due to a single gene mutation, and not all people with these mutations develop Parkinson's, suggesting that environmental factors also contribute to the likelihood of developing the disease.

About the chemicals
Researchers suspect that environmental
pollution affects the risk of Parkinson's.

TCE is a widely used metal degreaser (it also used to be a general anesthetic and coffee decaffeinating agent), while PERC is more commonly known as the dry cleaning fluid and often used in garment dry cleaning operations.

The occupations with the strongest link for TCE were the industrial machinery repairer and industrial worker categories.

TCE has also been linked to Parkinson's by other research groups. Researchers at the University of Kentucky, Lexington, and the Kangwon National University in South Korea have reported an association between TCE and Parkinson's in highly-exposed industrial workers, and have also demonstrated that TCE causes neurodegeneration in animal models.

About the study

The study involved 99 pairs of twins because they are so genetically similar and help in identifying environmental influences in disease.

The study team assessed the twins' lifetime work and hobby activities, specifically inquiring about occupational tasks such as electrical work, industrial machinery repair, and dry cleaning, which would potentially expose people to chemicals previously linked to Parkinson's.

The researchers also collected information on head injuries, which are suspected to increase Parkinson's risk, and smoking history, which is reported to decrease Parkinson's risk.

Expert evaluators, unaware of which study subjects had Parkinson's, reviewed this information and calculated lifelong exposure to six chemicals: TCE, PERC, carbon tetrachloride, n-hexane, xylene and toluene. Of these, TCE and PERC posed a notable risk for developing Parkinson's.

"The potential importance is great, since both solvents persist in the environment and are commonly used," said Samuel Goldman, M.D., M.P.H. in a press release. "Parkinson's was sixfold more common in twins exposed to TCE, and ninefold more common in twins exposed to TCE or PERC."
I-6500 is a powerful air cleaner.

There was also a trend toward a tenfold increase in Parkinson's disease in twins exposed to PERC alone.
However, one limitation of the research is the small number of individuals studied, the researchers warn.

Reduce chemical exposure at the workplace

In some industries, you have to deal with certain solvents or chemicals, but employers need to protect workers with a comprehensive Health and Safety program.

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