Wednesday, October 29, 2014

Study to assess breast cancer risk for female firefighters

Firefighters are exposed to flame retardants,
diesel exhaust and other toxic chemicals,
which may affect their health.
When firefighters rush out the firehouse doors, sirens screeching on the way to fight fires, they put their lives on the line in more ways than one.

In responding to roughly 28,000 fire calls a year, members of the San Francisco Fire Department are routinely exposed to flame retardants, diesel exhaust and other toxic chemicals that seep out of raging infernos and work their way into the air.

A growing body of evidence strongly suggests that exposure increases firefighters’ risk of developing cancer. But until now, studies have focused on men.

That’s about to change. Members of the San Francisco Fire Department are working with researchers at UC Berkeley, UCSF and the Silent Spring Institute to find out whether exposure to toxic chemicals increases the risks of breast cancer in female firefighters.

The project, known as the Women Firefighters Biomonitoring Collaborative Study, has been under way for about a year.

“Since breast cancer is a cancer that more commonly affects women, and because of anecdotal evidence that the firefighters have been experiencing (many cases of breast cancer), we wanted to see if there was a link,” said Jessica Trowbridge, a UC Berkeley researcher who is coordinating the study.

Trowbridge and her colleagues are gathering blood and urine samples from about 160 women — 80 San Francisco firefighters and 80 city office workers who will serve as the control group — to use in measuring chemical, hormone and melatonin levels.

They will also measure the lengths of the women’s telomeres, caps on the ends of chromosomes that are associated with aging and cancer, also thought to be related to chemical exposure and working demanding night shifts.

Firefighters in general have higher rates of cancer, especially respiratory, digestive and urinary system varieties, a recent National Institute for Occupational Safety and Health study found.

That study included women, but there weren't enough of them to draw robust conclusions about their cancer risks, according to the Centers for Disease Control and Prevention.

With about 225 female firefighters, San Francisco is better equipped than most cities for a study like this: Women make up about 13 percent of its firefighting population, said Heather Buren, a lieutenant and paramedic with the fire department who is working on the study.

In 2011, less than 5 percent of firefighters nationwide were women, according to the Bureau of Labor Statistics.

Researchers will also test for other chemicals that could contribute to higher rates of cancer in both groups of women, who are probably exposed to personal care and household products as well.

There has been a cultural shift with respect to chemical exposure. For one, firefighters now have better breathing masks, which they’re encouraged to wear for longer periods of time in toxic environments.

There are also rules prohibiting members of the department from storing their turnouts — the suits they wear to fight fires — in firehouse rooms where they eat and sleep.

The San Francisco Firefighters Cancer Prevention Foundation, which organizes screenings and promotes cancer prevention in the department, is partially responsible for those changes. It was formed in 2006 by Tony Stefani, a retired firefighter who himself fought cancer.

Researchers have nearly finished enrolling participants for the breast cancer study. They hope to have results published in two years. The women who participate in the study will be able to see their individual results when they are complete.

Source: San Francisco Gate. This article has been edited for length.

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